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KMID : 1225720120040030161
Allergy, Asthma & Immunology Research : AAIR
2012 Volume.4 No. 3 p.161 ~ p.164
A Case of Hypereosinophilic Syndrome Presenting With Multiorgan Infarctions Associated With Disseminated Intravascular Coagulation
Park Sun-Mi

Park Ji-Won
Kim Sung-Min
Koo Eun-Hee
Lee Jin-Young
Lee Chul-Su
Choi Dong-Chull
Lee Byung-Jae
Abstract
Thromboembolism is one of the most critical complications of hypereosinophilic syndrome (HES). We report here a case of multi-organ infarctions related to HES. A 23-year-old woman was referred to our hospital with hemoptysis. Not only pulmonary, but also renal and splenic infarctions were detected on computed tomography images. Blood tests showed profound peripheral eosinophilia. She was diagnosed with HES with disseminated intravascular coagulation (DIC). We initiated infusion of corticosteroids, which effectively suppressed peripheral eosinophilia. However, consumptive coagulopathy did not improve and intracerebral hemorrhage related to thrombosis then developed. Addition of interferon-alpha resulted in the correction of the DIC associated with HES.
KEYWORD
Hypereosinophilic syndrome, eosinophilia, thromboembolism, disseminated intravascular coagulation, consumptive coagulopathy, interferon-alpha
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